Validity of Hemodynamic Monitoring Using Inert Gas Rebreathing Method in Patients With Chronic Heart Failure and Those Implanted With a Left Ventricular Assist Device

Objective The present study assessed agreement between resting cardiac output estimated by inert gas rebreathing (IGR) and thermodilution methods in patients with heart failure those implanted a left ventricular assist device (LVAD). Methods Results Hemodynamic measurements were obtained 42 patients, 22 chronic 20 continuous flow LVAD (34 males, aged 50 ± 11 years). Measurements performed at rest using IGR methods. Cardiac derived not significantly different (4.4 0.9 L/min vs 4.7 0.8 L/min, P = .27) or 1.4 4.5 1.3 .75). There was strong relationship index (r 0.81, .001) stroke volume 0.75, .001). Bland–Altman analysis showed acceptable limits of for IGR, namely, the mean difference (lower upper agreement) –0.002 L/min/m2 (–0.65 to 0.66 L/min/m2), –0.14 (–0.78 0.49 L/min/m2) LVAD. Conclusions is valid method estimating should be used clinical practice complement evaluation management an